DDL 2014: Chemically-specific Characterization of Particulate in Inhalable Drug Products using Raman and Laser-induced Breakdown Spectroscopy
December 11, 2014 The impact of foreign particulate and agglomerates on dissolution profile and permeability of the inhalable drug particles within the sites of action (i.e. patient’s lungs) is critical. In this study, Raman Chemical Imaging (RCI) and Raman/ Laser-induced breakdown spectroscopy (LIBS) were used to investigate the Active Pharmaceutical…
2017 PDA Annual Meeting: Beyond the Count
Authors & ContributorsRebekah ByrneDavid ExlineEmily Landsperger
RDD 2013: Polymorph Identification of Drug Particles in Orally Inhaled and Nasal Drug Products
June 04, 2013 Authored by Oksana Olkhovyk, Ph.D., at Gateway Analytical , this poster presents new qualitative and semi-qualitative methods for the examination of size and polymorph drug particle identification in finished products. Specifically, its benefits for BA/BE testing is described using the model of fluticasone-containing nasal spray suspension formulation.…
AAPS 2012: Investigating the Miscibility of an API in Soluplus Dispersions by Raman Chemical Imaging Technique
October 18, 2012
IFPAC 2013 Presentation: Forensic Analysis of Foreign Particles in Pharmaceutical Materials
Authors & Contributors Rebekah Byrne
2014 IACP Conference: The Evolution of Gunshot Residue Analysis
Authors & Contributors David Exline Emily Landsperger Cara Plese November 19, 2014 Gunshot residue analysis is a common request in forensic laboratories with cases that question whether or not anindividual fired a firearm. When a firearm is fired, several types of residues are expelled from the openings on the firearm. Primer residues, specifically,…
DDL 2013: Raman-based Analysis of Dispersed Versus Aggregated Drug Particles in MDI Formulations for Chemically-specific Sizing and Polymorphic Purity Assessment
In this study, Raman Chemical...
2017 AAPS Drug Dissolution for Foreign Particulate Analysis: Overcoming Challenges of MCC in Nasal Sprays
Foreign particulate matter in drug...
RDD 2016: API-Specific Particle Size Distribution and Agglomerate Analysis using the rap.ID Single Particle Explorer (SPE)
The Active Pharmaceutical Ingredient (API)...